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If it is not illegal and not banned, why is it a story in the first place?
Pretty much any use of aspirin is legal, but it will still screw your liver all the way up if you take a bunch.
it's not a drug that should be used consistently over a long period of time.
Doctor 1: "Leeches!"
Doctor 2: "Mercury!"
Doctor 3: "Trepanning!"
I think the fact that there was dissension between players and among the medical staff on the way the trainer was using it is evidence that something wasn't kosher.
1. There are health concerns, eg liver disease, about long term high dosage NSAID use. With aspirin, those health concerns are balanced out by aspirin's potential benefits viz cardiovascular health, and also potentially (some types of) cancer.
2. Even putting aside concerns about health, there are also concerns from a sports performance standpoint. In the short term, obviously painkillers allow you to play / train through pain. But, in the long(er) term, painkillers (ie Cox2 inhibitors) can, and probably do, inhibit the mechanism(s) necessary for adaptation to training. In general, Cox2 inhibitors will inhibit prostaglandins. But surely that is a good thing, you say. Not necessarily. Prostaglandins, as a result of exercise training, are necessary to get macrophages to degrade damaged tissue. Those macrophages then release cytokines such as interleukin 6. But isn't interleukin 6 a bad thing? Again, not necessarily. Acute IL6 increases from exercise, as opposed to chronic elevated IL6 as seen in say type 2 diabetes or CVD, appears to be probably necessary to stimulate satellite cell proliferation and differentiation in response to exercise training. Interestingly, older men, in response to exercise training, have decreased, and also, slower IL6 response, and incresed SOCS3 (surpressor of cytokine signalling 3) response, compared to young men. More importantly, that decreased, and slower IL6 response, and increased SOCS3 response, occurs in conjuction with decreased satellite cell response to exercise.
3. That's why recovery from exercise is complicated. As scientists increasingly understand the molecular mechanisms of exercise adaptation, they are increasingly realising that "damage" from exercise is necessary for adaptation, and if you use (too much) various means that shut of those mechanisms, you don't get the positive adaptation. IOW, no pain, no gain.
What is it with the Red Sox and hiring flaming $#$!$!$? Is it really so very important to have a genius trainer that it's worth dividing the clubhouse and creating unnecessary controversy? Whatever happened to hiring a nice, competent person who makes conventional decisions and is easy to get along with?
As far as I know, there is no more reason to be concerned about long-term Toradol use than long-term Tylenol or Advil use.
There is much more reason to be concerned about long-term corticosteroid use (which has been going on for a long time in sports) than long-term NSAID use
As everyone knows, we’ve gone through quite a bit of change the last two years. We really had a two-year process of reorganizing the medical staff. This offseason was Year Two of two years,” said Cherington. “It was all done with the intent of putting not just the most talented group together, but a group that would work together seamlessly, put the players first and earn the players’ trust and develop credibility with the players. There’s a number of changes that have happened toward that goal. The irony is that if things are going well in that area, we’re not talking about it nearly as much as we have, and you’re not hearing from the medical staff. That’s our hope going forward, that we’re hearing from the guys in uniform a lot more and the guys in the training room less. That’s our expectation. Everything that I’ve seen, these stories that have been out there, they’re really about things that happened in the past and not things going on right now. Our focus is right now.”
Not trying to be rude, but having a hard time understanding why Matt Clement has been a persistent defender of Toradol in these threads.
Even after hearing from a pharmacologist (and others) about why it's a bad idea to be injected with high doses of high-wattage analgesics
MCOA is BTFs preeminent self-appointed propagandist/apologist for the Red Sox organization
It's not that I need to defend myself to Joey, exactly. It's just that he's once again confirming he is BTF's single worst poster by not understanding at all what I've said here.
MCOA is BTFs preeminent self-appointed propagandist/apologist for the Red Sox organization.
there is no clear performance advantage of using painkillers over not using painkillers.
There are guys whose entire careers would be impossible without painkillers. Painkillers render the value of every other performance enhancer a distant second.
Relationships between pitchers and their arms are unique — extremely, even excessively, focused partnerships full of fear and pain and trust and hope. The relationship starts early and can end badly. Anytime. Mike Pelfrey of the Mets is off for Tommy John elbow surgery. Michael Pineda had his shoulder repaired. Johan Santana is coming back from surgery. Medicine has made advances. Miracles happen. Still, ruin is always one pitch away, especially if you are already making those pitches in pain.
Once I started pitching, I’m not sure my left arm ever didn’t hurt. For more than three decades, whether in Little League or the minor leagues or Fenway Park in Boston, there was pain. Sharp or dull, in the elbow or at the shoulder. Throwing fastballs as a kid or junk as a lefty trying to stay in the big leagues, it all led to pain. It would be dulled by aspirin or beer or more powerful cocktails of medicine and booze. But it would never leave.
I told Steve that I took eight aspirin a day but that sometimes I needed a little more help. Anti-inflammatories, stuff like that. I started the season in the bullpen and got my first start April 22. Our routine was that after every start, I sunk my elbow in a bucket of ice (doubled as a beer cooler) for 20 to 30 minutes. A few cigarettes and beers later, no pain. Imagine. Not much other than that.
By then, my love affair with my changeup was in full bloom. Quite simply, it hurt less to throw. By June, we were eight or nine games up, and it was over for the rest of the N.L. East. But I had a problem: my elbow was flat-out quitting on me. Time to get in the jar. The team doctor examined me and said I needed to rest it. That wasn’t going to happen, I told him. I played the “this conversation never happened” card, and he respected my decision to take responsibility for the consequences. He prescribed the pills I needed.
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