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Schilling remembers one particular game, a 2002 Sunday getaway day in Milwaukee with the Arizona Diamondbacks.
"I slept on a pillow wrong," he said. "I woke up at 5:30 [a.m.]. I couldn't move my head. I went to the ballpark at 6:30 for a 1:30 [p.m.] game. Worked for four hours on it. I literally couldn't move my head. I went to the bullpen and started throwing and I didn't think there was any way I could pitch.
"Then the Toradol kicked in. I threw a one-hitter and struck out 17."
Though officials have tried to discredit Schilling’s story since he first told it last week, Schilling maintains he has no reason to fabricate the incident. Schilling said he didn’t tell investigators the entire truth because Beckett and others liked Reinold and, as a player on his way out of the game, he did not want to upset the clubhouse.
Even though it’s neither considered nor classified as a performance-enhancing drug, its ability to help pitchers perform isn’t in doubt
I really wish the drug company had chosen a different name than "Toradol". If people were saying, "injectable advil" - which is basically all Toradol is - I think there would be a very different public reaction
"The use of ketorolac is limited to 5 days for acute pain requiring opioid-level analgesia and can be administered intramuscularly, intravenously, or orally.....It is widely used in postoperative patients, but it should not be used for routine analgesia...
The black box warning for ketorolac stresses the possibility of serious adverse GI, renal, bleeding, and hypersensitivity reactions from the use of this potent NSAID analgesic."
All of them considered Toradol to be a strong but perfectly normal NSAID.
The reason that strength differences matter so much for opioids has to do with issues of dependence and resistance. Those issues don't apply for NSAIDs, as I understand it.
The "strength" of COX inhibitors does make a difference. The GI bleed and ulceration is due to the inhibition of COX 1 in the stomach and gut. The prostaglandins produced by COX 1 serve as cytoprotectants in 2 ways:
but NOT to be used routinely
This is also true of corticosteroids, isn't it? But pro sports teams, and especially baseball teams, appear to ignore the warnings when it comes to cortisone shots, too.
Conceivably, I suppose, they could have been using a much lower dose that that used for acute post-operative pain (I doubt it, though).
And the placebo effect that you mentioned could very well be operative here.
Also, on esophagitis in a 20-something athlete, she thinks drinking is a more likely cause than Toradol/advil side effects
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